Download Antibacterial Agents: Chemistry, Mode of Action, Mechanisms by Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley PDF

By Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley

Antibacterial brokers act opposed to bacterial an infection both by way of killing the bacterium or by way of arresting its development. They do that by way of focusing on bacterial DNA and its linked techniques, attacking bacterial metabolic techniques together with protein synthesis, or interfering with bacterial mobile wall synthesis and function.

Antibacterial Agents is a necessary advisor to this significant category of chemotherapeutic medications. Compounds are organised in line with their objective, which is helping the reader comprehend the mechanism of motion of those medications and the way resistance can come up. The booklet makes use of an built-in “lab-to-clinic” process which covers drug discovery, resource or synthesis, mode of motion, mechanisms of resistance, medical elements (including hyperlinks to present guidance, major drug interactions, cautions and contraindications), prodrugs and destiny improvements.

Agents lined include:

  • agents focusing on DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents
  • agents concentrating on metabolic strategies -  sulfonamide antibacterial brokers and trimethoprim
  • agents focusing on protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones
  • agents concentrating on mobilephone wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin

Antibacterial Agents will discover a position at the bookshelves of scholars of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

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Categories: Industrial Technical Chemistry